Creating a World with Missing Wild Types

8 April 2019

It occurs to me from endocrine disruptor residues in our bodies that we no longer have wild type genders in western culture; from pesticides, antibiotics, antiseptics, antivirals and vaccines we lose our wild type microbiomes and viromes, our wild type immune systems; from epigenetically active substances, GMOs and mutagenic substances and lateral gene transfer we lose our wild type genomes.

This is happening to us humans, our pets, our livestock and we are doing it to every living thing that is coming in contact with our airsheds, watersheds, agriculture, fisheries, waste disposal systems and commercial enterprise. Through climate change we are forcing countless species to adapt to a changing world and where that leads is probably to an extinction for many.

We are altering the course of evolution and haven’t a clue how much or with what overall long term ramifications. We do know there are massive mysterious declines and resistant superbugs and mysterious autoimmune disorders and widespread cancers in Western Cultures. Are these problems trying to send us a message?

What we should be doing is going to the jungle to visit lost tribes and Chimp bands and taking stool samples, skin swabs and oral swabs and also comparative studies of the immune systems of these folks/creatures to learn what we have lost in the developed/polluted world.

Jorma Jyrkkanen, jormabio@hotmail.com

facebook.com/whatsmymicrobiome.net

Evolution of mozaic operons by lateral gene transfer. https://www.ncbi.nlm.nih.gov/pubmed/12952534

Bactericidal antibiotics impacts. Mitochondrial dysfunction. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/?fbclid=IwAR2Kzu2ygqwZLea_KN8o6YA5crMJtPK9PtEn4bxGA1CPusKJoiKLYXOKuGE

Antibiotic resistance. https://www.sciencedirect.com/science/article/abs/pii/S1438422113000192

Protective microbes at risk from antibiotics, pesticides? Protective microbes provide an important complement to the host’s defence systems (Abt and Artis, 2013; Hooper et al., 2012; McFall-Ngai et al., 2013)

Vaccine obsession may be creating novel pathogen variants. https://www.quantamagazine.org/how-vaccines-can-drive-pathogens-to-evolve-20180510/

Tetracyclines disturb mitochondrial function across eukaryotes. https://www.sciencedirect.com/science/article/pii/S2211124715001801?fbclid=IwAR18zkstt0LPGdgVSMpi77w-gX1HPBMeWnMf-3U5GADpauIuTLVkgT1XSCo

Every chemical we produce and expose organisms to added to global biome environments may force mutations and natural selection in a potentially novel direction. These are not Wild types anymore. We humans were the selection pressure origin. https://news.harvard.edu/gazette/story/2014/02/evolution-in-real-time/

How do pesticides, antibiotics and gut microbes connect to the neurological axis? https://www.sciencedirect.com/science/article/pii/S1931312815001699